FIELD: chemistry.SUBSTANCE: invention relates to derivatives of hambogenic acid corresponding to structural formulae (I) or (II), where A is -CO- or -HC(OH)- R2 hydrogen or a straight or branched C1-C10 alkyl group R3 hydrogen or acyl group, substituted with C1-C10 alkyl group R is hydrogen or a straight or branched C1-C10 alkyl group R1 is selected from: -OR4, or in which R4 is selected from a group consisting of any of the following: hydrogen, straight or branched C1-C10 alkyl group or an alkyl group, possibly containing from 1 to 3 substituted groups, including oxygen, C1-C10 alkoxy group or with C1-C10 alkoxycarbonyl group R5 and R6 are independently selected from any of the following substituted groups: hydrogen straight or branched C1-C10 alkyl group or with C1-C10 alkyl group, possibly containing from 1 to 3 substituted groups, including oxygen, C1-C10 alkoxy group, C1-C10 alkoxyacyl group, C1-C10 alkyl group, substituted with phenyl s and t are integer positive numbers, and sum of s and t is a natural number from 2 to 4 m is 0, 1, 2 or 3 and represents a number of substituted groups with R7 rings n is 0, 1, 2 or 3 and represents B on the ring B is carbon, nitrogen or oxygen B is carbon, groups R7, R8 are identical to group R5 and R4, R3, R2, R1 and are not simultaneously hydrogen as indicated in Formula (I). Invention also relates to methods of producing compounds of formulae I and II and intermediate compounds and to anticancer pharmaceutical composition based on these compounds.EFFECT: in comparison with hambogenic acid derivatives hambogenic acid exhibit effective anticancer activity.13 cl, 5 dwg, 2 tbl, 28 exИзобретение относится к производным гамбогеновой кислоты, соответствующим структурным Формулам (I) или (II), где А является -СО- или -НС(ОН)- R2 водород или прямая или разветвленная C1-С10алкильная группа R3 водород или ацильная группа, замещенная C1-С10алкильной группой R водород или прямая или разветвленная C1-С10алкильная группаR1 выбран из:-