Thomas B. Ottoboni,Lee Ann Lynn Schillinger,Joseph Niemann
申请号：
US14213658
公开号：
US09446036B2
申请日:
2014.03.14
申请国别(地区):
US
年份:
2016
代理人:
摘要：
Delivery systems and compositions comprised of a biodegradable polyorthoester polymer, an aprotic solvent, and a drug are described. The solvent is selected to modulate release of drug from the composition, where, in some embodiments, the solvent is rapidly released after administration and provides a corresponding rapid rate of drug release. Alternatively, in other embodiments, the solvent is slowly released from the composition after its administration, and provides a correspondingly slow rate of drug release.
