Michael Almstetter,Michael Thormann,Andreas Treml,Roland Koestler,Nasser Yehia
申请号：
US15983423
公开号：
US20180305356A1
申请日:
2018.05.18
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention relates to novel compounds of formula (I)that are capable of inhibiting one or more kinases, especially SYK (Spleen Tyrosine Kinase), LRRK2 (Leucine-rich repeat kinase 2) and/or MYLK (Myosin light chain kinase) or mutants thereof. The compounds find applications in the treatment of a variety of diseases. These diseases include autoimmune diseases, inflammatory diseases, bone diseases, metabolic diseases, neurological and neurodegenerative diseases, cancer, cardiovascular diseases, allergies, asthma, alzheimer's disease, parkinson's disease, skin disorders, eye diseases, infectious diseases and hormone-related diseases.
