Hui Hong,Xiang Xu,Jiaxin Yu,Rajinder Singh,Ihab S. Darwish,Sambaiah Thota
申请号：
US14053325
公开号：
US09174964B2
申请日:
2013.10.14
申请国别(地区):
US
年份:
2015
代理人:
摘要：
Disclosed are carboxamide, sulfonamide and amine compounds including certain AMPK-activating piperidinylxoy-substituted 2,3-dihydro-1H-indene-1-amine compounds, as well as pharmaceutical compositions including them. One embodiment is a compound having the structurein which R1, R3,R4,R5,R14,R15,R17, G, Q, k, v, x and y are as described herein. In certain embodiments, a compound disclosed herein activates the AMPK pathway, and can be used to treat metabolism-related disorders and conditions.
