Elisabeth Buchdunger;Sandra Leta Siberman;Terence O'Reilly;Christian Bruns;Markus Wartmann;Gisbert Weckbecker
发明人:
Christian Bruns,Elisabeth Buchdunger,Terence O'Reilly,Sandra Leta Siberman,Markus Wartmann,Gisbert Weckbecker,Terence OReilly
申请号：
US13551079
公开号：
US20120283206A1
申请日:
2012.07.17
申请国别(地区):
US
年份:
2012
代理人:
摘要：
A method of treating a warm-blooded animal, especially a human, having a proliferative disease or acute or chronic transplant rejection comprising administering to the animal a combination which comprises (a) N-{5-[4-(4-methyl-piperazino-methyl)-benzoylamido]-2-methylphenyl}-4-(3-pyridyl)-2-pyrimidine-amine and (b) a chemotherapeutic agent selected from antineoplastic agents, especially as defined herein, and agents effective in treating acute or chronic transplant rejection； a combination comprising (a) and (b) as defined above and optionally at least one pharmaceutically acceptable carrier for simultaneous, separate or sequential use, in particular for the delay of progression or treatment of a proliferative disease, especially a solid tumor disease.
