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DIHYDROPYRROLIDINOPYRIMIDINES COMME INHIBITEURS DE KINASE
专利权人:
NOVARTIS AG
发明人:
申请号:
EP13771007.5
公开号:
EP2897961B1
申请日:
2013.09.17
申请国别(地区):
EP
年份:
2016
代理人:
摘要:
The present invention provides compounds of Formula (I) and pharmaceutically acceptable salts thereof; as further described herein. The present invention further provides pharmaceutical compositions comprising these compounds, and combinations comprising these compounds combined with or used with a therapeutic co-agent, as well as therapeutic uses of these compounds and compositions. These are useful in the treatment of diseases such as cancer that are associated with activation of ERK1 and/or ERK2, and especially for MAPK pathway dependent cancers showing resistance to Raf and/or MEK inhibitory cancer therapeutics
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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