Device (1) for controlling the intake of drugs, applicable to a package (50) containing one or more doses of a drug, said device (1) comprising: sensor means (21) adapted to detect the vibrational energy transferred to said package (50), in response of interactions of a user with said package (50) to release one or more doses of said drug； a processor (25) connected to said sensor means (21)； wherein said processor (25) is configured to calculate intake information of said drug on the basis of the vibrational energy detected by said sensor means (21)； system for signalling the intake of drugs； system (100) for controlling the intake of drugs and drug accessories (10, 20, 30, 40, 40b) comprising such device (1) applicable to drug packages.
