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siRNA molecule for inhibiting growth of melanin and application thereof
专利权人:
Jiangsu Genecon Biotechnologies Co.; Ltd.
发明人:
Yuanyuan Zhu,Tiejun Li
申请号:
US14354532
公开号:
US09045753B2
申请日:
2012.10.09
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Provided is a double-chain siRNA molecule targeting a microphthalmia-associated transcription factor MITF coding gene. A sense strand of the siRNA molecule has a sequence of SEQ ID NO: 3 and an anti-sense strand has a sequence of SEQ ID NO: 4, and the anti-sense strand specifically binds to mRNA of the MITF coding gene, to degrade the mRNA, thereby reducing the synthesis of melanin. Further provided is an application of the siRNA molecule in freckle whitening cosmetics or the preparation of medicines for treatment of diseases related to melanin gene.
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中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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