A means and method that forms and maintains an enclosed sterile environment that then is able to sterilize all that is within the enclosure in order to facilitate making a sterile or aseptic connection and keeping it sterile or aseptic. Connection may be between a container of material to a and through a terminus using tubes or hoses interspersed with a connector or connectors. The means and method are substantially comprised of an enclosure to be filled with a sterilant, that by various means attaches to or are parts of connectors, other connectors, a sterilant, a method of propelling the sterilant and other propelling mechanisms as required. The sterilant surrounds the critical parts to make all that is within an enclosure including the connectors and other parts within the enclosure as well as possibly through hoses or tubes to a terminus and through it to the point a material exits the terminus while making a connection sterile or aseptic. It is also the means of repeating the process of connecting a source to a terminus sterile or aseptic. Other aspects may also include maintaining sterility of other points of connection.