In an embodiment, the present disclosure pertains to a dietary supplement including berberine in an amount up to about 1500 mg, cinnamon in an amount up to about 300 mg, chromium in an amount up to about 300 mcg, milk thistle in an amount up to about 150 mg, and pyrroloquinoline quinone disodium (PQQ) in an amount up to about 30 mg. Additionally, the present disclosure relates to a method for managing weight, maintaining healthy blood sugar levels, preventing diabetes, or alleviating symptoms associated with diabetes, including administering a composition to a subject. In some embodiments, the composition includes berberine in an amount up to about 1500 mg, cinnamon in an amount up to about 300 mg, chromium in an amount up to about 300 mcg, milk thistle in an amount up to about 150 mg, and PQQ in an amount up to about 30 mg.
