PRSS2 INHIBITION

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专利权人:

Children's Medical Center Corporation

发明人:

Randolph S. Watnick

申请号：

US16496142

公开号：

US20200031906A1

申请日:

2018.03.22

申请国别(地区):

US

年份:

2020

代理人:

摘要：

Provided herein are agents that inhibit the function (e.g., the ability to repress Tsp-1) of Protease, Serine 2 (PRSS2) by inhibiting the binding of PRSS2 to LRP1. Further provided herein are control agents that bind to binding domain I of LRP1 and mimic the activity of prosaposin in stimulating Tsp-1 Methods of using these agents in treating cancer are also provided.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/