An endoscope treatment tool includes a treatment portion, a manipulation portion, and a manipulation wire connecting the treatment portion and the manipulation portion, the manipulation portion includes a manipulation portion main body, a shaft, a clutch plate having a through-hole into which the shaft is slidably inserted, a manipulation member slidably attached to the manipulation portion main body, and a force adjustment member compressed in accordance with manipulation of the manipulation member, and the clutch plate is inclined with respect to the shaft in accordance with compression of the force adjustment member, and thereby the manipulation member is fixed to the manipulation portion main body by the clutch plate which is fixed to the shaft so as not to slide with respect to the shaft.
