Cząsteczki, które selektywnie aktywują regulatorowe komórki T, do leczenia chorób autoimmunologicznych

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专利权人:

Delinia; Inc.

发明人:

GREVE, JEFFREY

申请号：

PL15824955

公开号：

PL3172227T3

申请日:

2015.07.20

申请国别(地区):

PL

年份:

2020

代理人:

摘要：

This invention provides for a fusion protein between an IL2αβγ Selective Agonist protein (IL2 Selective Agonist) and a IgG Fc protein. The IL2 Selective Agonist moiety provides a therapeutic activity by selectively activating the IE2αβγ form of the receptor, thus selectively stimulating Tregs. The Fc moiety provides a prolonged circulating half-life compared to the circulating half-life of IL-2 or an IL2 Selective Agonist protein.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/