PROBLEM TO BE SOLVED: To provide a vehicle disinfection device which is excellent in the reactivity of injection of an antiseptic solution.SOLUTION: A vehicle disinfection device includes antiseptic solution injection means 41 which injects an antiseptic solution toward a vehicle and control means which controls the antiseptic solution injection means 41. The antiseptic solution injection means 41 has loop-shaped nozzle mounting pipes 53, 63 through which the antiseptic solution circulates. Nozzles 56, 57, 66, 67 are mounted to the nozzle mounting pipes 53, 63 through pressure valves. The control means increases the pressure of the antiseptic solution in the nozzle mounting pipes 53, 63 to a set pressure to inject the antiseptic solution from the nozzles 56, 57, 66, 67.