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SEL DE TOSYLATE DE TRANS-N-ISOBUTYL-3-FLUORO-3-[3-FLUORO-4-(PYRROLIDIN-1-YLMETHYL)PHENYL]CYCLOBUTANECARBOXAMIDE
专利权人:
PFIZER INC.
发明人:
WAGER, TRAVIS T.,BUTLER, TODD WILLIAM
申请号:
CA2708043
公开号:
CA2708043C
申请日:
2008.12.04
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
The present invention is directed to the tosylate salt of trans-N-isobutyl- 3-fluoro-3-[3-fluoro-4-(pyrrolidin-1-yl-methyl)-phenyl]-cyclobutanecarboxamide Formula (1): to solvates (e.g.,hydrates) thereof, to polymorphs thereof, to pharmaceuticalcompositions thereof and to a method of treating depression, mood disorders,schizophrenia, anxiety disorders, cognitive disorders,Alzheimer's disease, attention-deficit disorder (ADD), attention-deficithyperactivity disorder (ADHD), psychotic disorders, sleepdisorders, obesity, dizziness, epilepsy, motion sickness, respiratorydiseases, allergy, allergy-induced airway responses, allergicrhinitis, nasal congestion, allergic congestion, congestion, hypotension,cardiovascular disease, diseases of the G1 tract, hyper- andhypo-motility and acidic secretion of the gastro-intestinal tract comprisingadministering a therapeutically effective amount thereof.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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