#$%^&*AU2012201321A120120329.pdf#####ABSTRACT OF THE DISCLOSURE Methods for using death receptor ligands, such as Apo-2 ligand/TRAIL polypeptides or death receptor antibodies, and EGFR inhibitors to treat pathological conditions such as cancer are 5 provided. Embodiments of the invention include methods of using Apo2L/TRAIL or death receptor antibodies such as DR5 antibodies and DR4 antibodies in combination with EGFR inhibitors, such as TarcevaTm. 3168883 1 (GHMtrters P72533 AU.1