Provided herein are systems and methods (i.e., utilities) that are directed to correcting misalignments or offsets between a series or sequence of medical images. The utility corrects offsets between a series of medical images obtained where an imaging device (e.g., ultrasound probe) is supported by a positioning mechanism where there is misalignment between an imaging axis or other reference point of the imaging device and the axis of movement of the positioning device. The determination of this offset between these axis allows for calculating a transformation that allows for placing each of the series images into a common frame of reference.
