The present invention provides inhibiting or weakening the method for the tumour growth in object with what, by applying IL-6 antagonists to object. In certain embodiments, method of the invention what inhibits the growth of the anti-vegf resistance tumor in object. IL-6 antagonists can be the antibody for for example specifically binding IL-6R. IL-6 antagonists can be applied with VEGF antagonist and/or EGFR antagonist-combinations.本發明提供了用於抑制或减弱對象中的腫瘤生長的方法，通過向對象施用IL-6拮抗劑。在某些實施方案中，本發明的方法用於抑制對象中的抗VEGF抗性腫瘤的生長。IL-6拮抗劑可以是例如特異性結合IL-6R的抗體。IL-6拮抗劑可以與VEGF拮抗劑和／或EGFR拮抗劑組合施用。
