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NOVEL 2-AMINO-4-PYRAZOLYL-THIAZOLE DERIVATIVES AND THEIR USE AS ALLOSTERIC MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS
专利权人:
Christelle Boléa
发明人:
Christelle Boléa,Sylvain Celanire,Cédric Boudou,Lam Tang,Jean-Philippe Rocher,Nigel John Liverton
申请号:
US13808899
公开号:
US20130210809A1
申请日:
2011.07.12
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention relates to novel compounds of Formula (1), wherein M, A and B are defined as in Formula (I) invention compounds are modulators of metabotropic glutamate receptors-subtype 4 (“mGluR4”) which are useful for the treatment or prevention of central nervous system disorders as well other disorders modulated by mGluR4 receptors. The invention is also directed to pharmaceutical compositions and the use of such compounds in the manufacture of medicaments, as well as to the use of such compounds for the prevention and treatment of such diseases in which mGluR4 is involved.
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