The present invention relates to a medicament delivery device for dispensing a dose of medicament from a retained cartridge wherein the medicament delivery device defines a distal medicament outlet end and an opposite proximal end. The medicament delivery device includes a distal housing component (110), which holds a cartridge (113) comprising axially disposed and slidable pistons and a liquid agent therein, and a cartridge (113) for dispensing a dose, And a proximal housing component (101) comprising a piston rod for exerting a force in a distal direction with respect to the piston of the piston, and containing a dosing and dispensing mechanism. The distal housing component (110) and the proximal housing component (101) can be displaced axially relative to one another in order to reduce the axial distance between the piston rod (120) and the piston of the cartridge (113) As shown in FIG. One of the distal housing component (110) and the proximal housing component (101) comprises a threaded adjustment component (103) and the threaded adjustment component (103) comprises a distal housing component ) And the proximal housing component (101), and defines a first thread (103b), the first thread (103b) being held in the axial fixed position on said one of the proximal housing component (101) Is in threaded engagement with a second thread (110b) defined by the other of the distal housing component (110) and the proximal housing component (101). After displacement, the threaded adjustment component (103) is rotatably anchored so that the adjustment component (103) can not rotate without the use of the tool.(Fig.本発明は、保持されているカートリッジから一用量の薬剤を吐出するための薬剤送達装置に関し、薬剤送達装置は、遠位薬剤出口端部および反対側の近位端部を画定している。薬剤送達装置は、その中に軸方向に配置されてスライド可能なピストンと液剤を備えるカートリッジ(113)を保持する、遠位ハウジングコンポーネント(110)と、一用量を吐出するためにカートリッジ(113)のピストンに対して遠位方向に力を及ぼすためのピストンロッドを備え、用量設定および吐出機構を収容する近位ハウジングコンポーネント(101)とを備える。遠位ハウジングコンポーネント(110)および近位ハウジングコンポーネント(101)が、ピストンロッド(120)とカートリッジ(113)のピストンとの間の軸方向距離を低減するために、互いに対して軸方向に変位可能に配置されている。遠位
