Therapeutic multi-peptides t specific immune therapy for treatment of brain metastasis

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专利权人:

OSE IMMUNOTHERAPEUTICS

发明人:

Costantini, Dominique

申请号：

NZ72951414

公开号：

NZ729514A

申请日:

2014.11.06

申请国别(地区):

NZ

年份:

2019

代理人:

摘要：

The present invention relates to a peptide vaccine composition OSE-2101 for treatment of brain metastasis in HLA-A2 positive patients, which comprises the peptides RLLQETELV (SEQ ID No 1), YLQLVFGIEV (SEQ ID No 2), LLTFWNPPV (SEQ ID No 3), KVFGSLAFV (SEQ ID No 4), KLBPVQLWV (SEQ ID No 5, with B indicating α-aminoisobutyric acid), SMPPPGTRV (SEQ ID No 6), IMIGHLVGV (SEQ ID No 7), KVAEIVHFL (SEQ ID No 8), YLSGADLNL (SEQ ID No 9), aKXVAAWTLKAAa (SEQ ID No 10, with X and a respectively indicating cyclohexylalanine and d-alanine).

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