Cosmetic use of a synergistic combination (A) of a C-glycoside derivative (I) with ascorbic acid (II), its derivatives or analogs to treat or prevent the chronobiologic or photo-induced aging signs of body/face skin. Independent claims are included for: (1) the composition (A) i.e. optionally being anhydrous； and (2) a cosmetic treatment of the body/face skin, including scalp, comprising applying the composition to the skin. ACTIVITY : Dermatological. MECHANISM OF ACTION : Procollagen-1 synthesis stimulator. The ability of the combination in improving the synthesis of procollagen-1 was tested. The results showed that the combination of C-glycoside derivative with ascorbic acid exhibited a synthesis rate of 1049, while the synthesis rate by each of C-glycoside derivative and ascorbic acid alone and by the control were 100, 96 and 887, respectively.
