This invention guranisetoron or that medicine the composition for prescribing inside the nasal cavity of the approved possible salt offers study. The composition where this invention is desirable takes the form of the water liquid medicine. The composition of this invention the Quito sun, being optional, includes the salt of that salt or the derivative or the derivative of the Quito sun. This composition evil intention and/or can use for the remedy of vomiting or prevention.< Selective figure >Figure 1本発明は、グラニセトロン又はその薬剤学的に許容可能な塩の鼻腔内投与のための組成物を提供する。本発明の好ましい組成物は水性液剤の形態をとる。本発明の組成物はキトサン、その塩又は誘導体、又はキトサンの誘導体の塩を任意で含む。この組成物は悪心及び/又は嘔吐の治療又は予防に使用することができる。【選択図】図1