ZEBRA BIOLOGICS, INC;THE SCRIPPS RESEARCH INSTITUTE
发明人:
LERNER, RICHARD A.,LINDSAY, RONALD M.,XIE, JIA
申请号：
CA3022915
公开号：
CA3022915A1
申请日:
2017.05.02
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
The invention provides TrkB agonist antibodies or antigen-binding fragments that specifically enhance TrkB signaling activities. The invention also provides therapeutic methods of using such antibodies for promoting survival and regeneration of retinal ganglion cells, and for treating or preventing subjects suffering from or at risk of developing various neurodegenerative coxiditions such as glaucoma.
