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NOVOS BIOMATERIAIS, SUA PREPARAÇÃO E UTILIZAÇÃO
专利权人:
NOVARTIS AG
发明人:
LAJOS SZENTE,CHRISTIAN SCHOCH,GYOERGY LAJOS KIS,JOZSEF SZEJTLI
申请号:
PT03720497
公开号:
PT1499361E
申请日:
2003.04.17
申请国别(地区):
PT
年份:
2012
代理人:
摘要:
The present invention relates to novel materials, particularly biomaterials, in form of a precipitate, comprising at least an anionic polymeric component which is as such soluble in water and an amphiphilic ammonium-type component, which precipitate is obtainable by a process including the following steps: 1. contacting the anionic polymeric component and an cyclodextrin component in an aqueous medium, and 2. adding to the mixture obtained in step 1 said amphiphilic ammonium-type component, wherein said components are present in amounts effective to form said precipitate, and preferably to corresponding precipitates additionally comprising said cyclodextrin component. Both types of precipitates may optionally comprise one or more further components. The precipitates are particularly useful as controlled-release depot formulations suitable for long-lasting delivery of said further components. The further components incorporated into the precipitates can be pharmaceutical compounds, pesticides, agrochemicals, colorants, diagnostics, enzymes, foodstuffs etc.
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