BINCH, HAYLEY,BRENCHLEY, GUY,GOLEC, JULIAN M. C.,KNEGTEL, RONALD,MORTIMORE, MICHAEL,PATEL, SANJAY,RUTHERFORD, ALISTAIR
申请号：
CA2473986
公开号：
CA2473986C
申请日:
2003.01.23
申请国别(地区):
CA
年份:
2012
代理人:
摘要：
The present invention provides compounds of formula (I), or a pharmaceuticallyacceptable derivative thereof, wherein R1, R2, V1, V2 and V3 are as describedin the specification. These compounds are inhibitors of protein kinase,particularly inhibitors of AKT, PKA, PDK1, p70S6K, or ROCK kinase, mammalianprotein kinases involved in proliferative and neurodegenerative disorders. Theinvention also provides pharmaceutical compositions comprising the compoundsof the invention and methods of utilizing those compositions in the treatmentof various disorders.
