The invention relates to a device (1) for reconstituting a pharmaceutical composition from at least a first component contained in a first container (2A) and a second component contained in a second container (2B), comprising: €¢ a fluidic unit (100) comprising: - a first connector (101) coupled to the first container (2A), - a second connector (102) coupled to the second container (2B), - a pump (103), - a fluidic circuit (104) connecting the first connector (101), the second connector (102) and the pump (103), wherein the first connector (101) comprises a crankpin (1011) in rotating engagement within a body (1010), said crankpin comprising a unique axial port (1011A) intended to fluidically couple to the first container, a radial port (1011 B) fluidically connected to said axial port (1011A), and at least one channel (1011C) arranged therein so as to cooperate with the radial ports of the body (1010) to selectively connect the axial port (1011A) of the first connector with at least one channel portion of the fluidic circuit (104) depending on the angular position of the crankpin (1011) with respect to the body (1010), €¢ a power unit (200) releasably coupled to the fluidic unit (100), comprising: - a power mechanism (203) for actuating the pump, - transmission means connected between an actuator and the crankpin (1011) for rotating the first container (2A).