Yeh-Long Chen,Tian-Lu Cheng,Cherng-Chyi Tzeng,Chih-Hua Tseng,Ta-Chun Cheng,Kai-Wen Cheng,Wei-Fen Luo
申请号：
US16711623
公开号：
US20200113878A1
申请日:
2019.12.12
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present invention provides novel pyrazolo[4,3-c]quinoline derivatives exhibiting specifically inhibition activity to microbiota β-glucuronidase, whereby providing potent activities to prevent chemotherapy-induced diarrhea (CID) of cancers. Therefore, the compounds of the present invention can be used as (1) chemotherapy-adjuvant to prevent chemotherapy-induced diarrhea (CID) and enhance chemotherapeutic efficiency of cancers； (2) health-food supplement to prevent the carcinogens induced colon carcinoma.
