NOUVELLE CONSTRUCTION D'ARN ET METHODES D'UTILISATION DE CETTE DERNIERE POUR AMELIORER LES EFFETS THERAPEUTIQUES DE CELLULES CYTOTOXIQUES ET DE CELLULES SOUCHES
The present invention comprises Rig I agonists for enhancing the effects of cytotoxic cells and stem Cells. The Rig I agonists can be used in vivo as small molecule therapeutics or in vitro to enhance cells for adoptive cell transfer. Applications include cancer therapy, immune system enhancement, chronic viral infection and treatment of viral induced inflammation and enhancement of virus based therapies.
