SCHULZE, Volker V,KOPPITZ, Marcus M,KOSEMUND, Dirk D,SCHIROK, Hartmut H,BADER, Benjamin B,LIENAU, Philip P,WENGNER, Antje, Margret AM,BRIEM, Hans H,HOLTON, Simon S,SIEMEISTER, Gerhard G,PRECHTL, Stefa,.舒爾策,.科皮茨,.科澤蒙德,.斯基洛克,.巴德爾,.利瑙,.溫內爾,.布里姆,HOLTON, Sim
申请号：
HK13105127.0
公开号：
HK1178153B
申请日:
2013.04.27
申请国别(地区):
HK
年份:
2016
代理人:
摘要：
The present invention relates to triazolopyridine compounds of general formula (I) which are Monopolar Spindle 1 kinase (Mps-1 or TTK) inhibitors: in which R 1 , R 2 , R 3 , R 4 , and R 5 are as given in the description and in the claims, to methods of preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds, to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of proliferative diseases, as well as to intermediate compounds useful in the preparation of said compounds.
