As for this invention, being something which offers the medicine which possesses the control of prevention and development of occurrence of the intestinal polyp which has a possibility of becoming the parent of the colon cancer and curative effect, general system[Conversion 1](In formula, as for R the low-grade alkyl group and as for X the halogen atom is shown.)So the carboxylic acid amide compound which is displayed, especially, 4 - jietokishihosuhuinoirumechiru - N- (4 - buromo - 2 - cyano phenyl) it relates to the intestinal polyp inhibiter which contains benzamide as the active ingredient.本発明は、大腸癌の母体となるおそれのある腸ポリープの発生の予防、進展の抑制および治療効果を有する薬剤を提供するものであって、一般式[化1](式中、Rは低級アルキル基およびXはハロゲン原子を示す。)で表されるカルボン酸アミド化合物、特に、4-ジエトキシホスフィノイルメチル-N-(4-ブロモ-2-シアノフェニル)ベンズアミドを有効成分として含有する腸ポリープ抑制剤に関わる。