Thomas Tötterman,Linda Sandin,Angelica Loskog,Sara Mangsbo,Peter Ellmark
申请号:
US13510565
公开号:
US20130004483A1
申请日:
2010.11.17
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention provides an immunomodulatory agent for use in the local treatment of tumours, wherein the treatment comprises patient-specific optimisation of the dose of the immunomodulatory agent to identify the maximum therapeutic dose that does not induce an increase in the number of local regulatory T cells (Treg cells) in the patient The invention further provides methods for the local treatment of tumours as well as methods for optimising treatments for the same