University of Pittsburgh - Of the Commonwealth System of Higher Education
发明人:
Thomas Payne,Ronald Jankowski,Ryan Pruchnic,Michael B. Chancellor
申请号：
US15347308
公开号：
US20170209495A1
申请日:
2016.11.09
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present invention provides muscle-derived progenitor cells (MDCs) that show long-term survival following transplantation into body tissues and which can augment soft tissue following introduction into a site of soft tissue. Also provided are methods of isolating MDCs. The invention further provides methods of using compositions comprising MDCs for the augmentation and bulking of mammalian, including human, soft tissues in the treatment of various cosmetic or functional conditions, including malformation, injury, weakness, disease, or dysfunction. The invention also relates to uses of MDCs for the treatment of cosmetic or functional conditions, including, but not limited to skeletal muscle weakness, muscular dystrophy, muscle atrophy, spasticity, myoclonus and myalgia. The invention also relates to the novel use of MDCs for the increase of skeletal muscle.
