Gene therapy can be used to overexpress genes. By overexpressing normal genes,the mutatedcounterpart (mutant genes) that are created in our body would bedownregulated. Since mutated genes(the causes of many genetic disorders) are decreased, the genetic diseases canbe cured. Try usingdifferent genes and overexpress, then the mutant counterpart would decreasedue to a negativefeedback mechanism. For example, our body can sense that we have alot ofglycogen in our body. Theamount of glycogen would be decreased and be transformed into otherform.Another example isacetylcholine. If we have many acetylcholine being produced. The body wouldsend a negative feedbackmechanism to destroy or not produce any more acetylcholine.