INC.;ATON PHARMA, INC.;LOUISIANA STATE UNIVERSITY AGRICULTURAL AND MECHANICAL COLLEGE;ATON PHARMA
发明人:
JACOB, JEAN THERESA,HALLORAN, KEVIN JOHN,MCKEE, YURI
申请号：
EP10827563
公开号：
EP2493459A4
申请日:
2010.10.29
申请国别(地区):
EP
年份:
2013
代理人:
摘要：
A method of forming an ocular delivery device includes exposing a solid, shaped cellulose polymer to a solution including an active pharmaceutical ingredient (API) and a solvent capable of solubilizing the API, wherein the polymer absorbs at least a portion of the solution, including the API and solvent. The method may further include removing at least a portion of the absorbed solvent from the polymer by allowing the absorbed solvent to evaporate from the polymer or by drying the polymer. A variety of cellulose polymers may be used, including hydroxypropyl cellulose. A variety of APIs may be used, including Cyclosporine, Tobramycin and Vancomycin. Ocular delivery devices prepared by the methods may be used to treat a variety of eye disorders.
