A venous valve prosthetic implant for treatment of venous disease may include an expandable anchoring frame a valve seat attached to the anchoring frame a ball retention member attached to the anchoring frame and a ball disposed within the lumen of the anchoring frame between the valve seat and the ball retention member. The anchoring frame may include a first end a second end and a middle valve portion where the middle valve portion expands to a smaller diameter than a diameter of either the first end or the second end. The ball may move back and forth within the middle valve portion between a fully open position and a fully closed position.
