Wet granulation tableting method using low-substituted hydroxypropylcellulose aqueous dispersion

• 收藏
• 分享

专利权人:

信越化学工業株式会社

发明人:

丸山 直亮

申请号：

JP2010013384

公开号：

JP5753661B2

申请日:

2010.01.25

申请国别(地区):

JP

年份:

2015

代理人:

摘要：

Provided is a method for preparing a tablet having high tablet hardness and an excellent disintegration property even if low-substituted hydroxypropyl cellulose is added in a relatively small amount. More specifically, provided is a method for preparing a tablet comprising steps of granulating while spraying an aqueous dispersion of low-substituted hydroxypropyl cellulose having a degree of hydroxypropoxyl group substitution ranging from 5 to 16% by weight to a tablet-forming composition and tableting the resulting granules.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/