PURPOSE: A pharmaceutical composition for preventing and treating degenerative brain diseases is provided to have neuroprotective effect using an Astilbe chinensis extract and to prevent and/or treat various degenerative brain diseases. CONSTITUTION: A pharmaceutical composition for preventing and treating degenerative brain diseases contains an Astilbe chinensis extract as an active ingredient. The degenerative brain diseases are selected among stroke, apoplexy, dementia, Alzheimer's disease, Parkinson's disease, Huntington's chorea, Pick's disease, and Creutzfeldt-Jakob disease. The extract is prepared from Astilbe chinensis roots using water, alcohol, or a mixture thereof. [Reference numerals] (AA) Normal group； (BB) Astilbe chinesis본 발명은 노루오줌 추출물을 유효성분으로 함유하는 퇴행성 뇌질환 예방 및 치료용 약학적 조성물을 제공한다. 본 발명의 노루오줌 추출물은 뇌신경세포 보호효과를 가지며, 따라서 다양한 퇴행성 뇌질환을 예방 및/또는 치료하는 작용효과를 나타낸다.
