The present invention without changing the characteristics of a biological fluid applied to provide a selective hydrogenation instruments that can provide the hydrogen-containing biological fluid applied. The A hydrogen generating system having the hydrogen generating agent as essential components, is housed in the hydrogen bubble formation member having a gas-liquid separation unit that includes a valve of a gas permeable membrane or closure, the hydrogen generated in the hydrogen bubble formation inside Through the reacting system and the generated water, the hydrogen gas generated in the hydrogen bubble formation body, through the gas-liquid separator to obtain a hydrogen-containing biological application liquid by feeding the biological application solution. [Selection Figure] Figure 1B【課題】生体適用液の特性を変えることなく、水素含有生体適用液を得ることができる選択的水素添加器具を提供する。【解決手段】水素発生剤を必須成分とする水素発生系を、ガス透過膜または開閉式の弁を含む気液分離部を有する水素気泡形成体に収容し、該水素気泡形成体内において前記水素発生系と発生用水を反応させることを通じて、該水素気泡形成体内に発生した水素ガスを、前記気液分離部を介して、生体適用液に送り込むことで水素含有生体適用液を得る。【選択図】 図1B