PURPOSE: A composition containing hyaluronic acid for preventing and treating osteoporosis is provided to induce the generation of collagen in a skin tissue.CONSTITUTION: A pharmaceutical composition for preventing and treating osteoporosis contains hyaluronic acid such as high molecular hyaluronic acid, middle molecular hyaluronic acid, and low molecular hyaluronic acid as active ingredients. The high molecular hyaluronic acid is prepared by the fermentation of the hyaluronic acid with microbes. The middle molecular hyaluronic acid and low molecular hyaluronic acid are prepared by an enzymatic method using the high molecular hyaluronic acid. The high molecular hyaluronic acid, the middle molecular hyaluronic acid, and the low molecular hyaluronic acid increase bone density and collagen, and prevent and treat osteoporosis.COPYRIGHT KIPO 2013본 발명은 히아루론산 즉 고분자히알루론산, 중분자히알루론산 및 저분자히알루론산을 유효성분으로 함유하는 골다공증의 예방, 치료, 또는 개선에 관한 것이며, 피부조직 내에 콜라겐 생성을 유도하며 특히 중분자히알루론산이 골다공증의 예방 또는 치료에 유용하게 사용될 수 있다.
