Kevin G Peters,Robert Shalwitz,John Janusz,Alexander Duncan Smith
申请号:
GB201709419
公开号:
GB2549865B
申请日:
2014.03.14
申请国别(地区):
GB
年份:
2018
代理人:
摘要:
Disclosed herein are compounds effective for activation of Tie-2 and inhibition of HPTP-beta. The compounds can provide effective therapy for conditions associated with angiogenesis, for example, ocular conditions. Formulations for increased solubility are disclosed. Combination therapy with antibodies and PK/PD data are also disclosed.