Provided are methods for preventing and treating inflammation and organ injuryafter ischemia/reperfusion, andmethods for treating lung injury, comprising administering a milk fat globuleepidermal growth factor-factor VIII (MFG-E8) to asubject. Also provided are pharmaceutical compositions comprising MFG-E8 indosage form for preventing and treatinginflammation and organ injury after ischemia/reperfusion, and for treatinglung injury, and methods of preparing a pharmaceutical compositionfor preventing and treating inflammation and organ injury afterischemia/reperfusion, and for treating lung injury, comprisingformulating MFG-E8 in a pharmaceutical composition.
