William S. M. Wold,Karoly Toth,Konstantin Doronin,Ann E. Tollefson
申请号：
US12561016
公开号：
US08658610B2
申请日:
2009.09.16
申请国别(地区):
US
年份:
2014
代理人:
摘要：
Novel vectors which are replication competent in neoplastic cells and which overexpress an adenovirus death protein are disclosed. Some of the disclosed vectors are replication-restricted to neoplastic cells or to neoplastic alveolar type II cells. Compositions and methods for promoting the death of neoplastic cells using these replication-competent vectors are also disclosed.
