A fluid transfer device (410) comprising a housing (412) having an exterior wall (422), a plurality of pairs of slots (428, 430) formed in the exterior wall, each one of the pairs of slots being diametrically opposed to each other； a needle hub (414) having an exterior wall (56, 58) and an interior wall (472) extending interiorly across the exterior wall (456, 458), to thereby form upper and lower compartments (492, 494) a first needle (474) extending upwardly from the interior wall (472), into the upper compartment (492) a second needle (476) extending downwardly from the interior wall into the lower compartment (494), the interior wall (472) having an opening therein to form a fluid passageway (478)； a first cartridge (416) having a plunger and a pierceable cap (490)； a second cartridge (480) having a plunger and a pierceable cap (484)； a base member (418), the member having a base bottom wall (446), a plunger wall (440) extending upwardly from the base bottom wall； and the arrangement being such that the first cartridge (416) is inserted into the base member (418) such that the plunger seats on the plunger rod (450), and the second cartridge (480) is in the housing (412) with the pierceable cap (484) of the second cartridge (480) facing the first needle (474).
