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Single domain VHH antibodies against Von Willebrand Factor
专利权人:
Karen Silence
发明人:
Karen Silence
申请号:
US12822729
公开号:
US08372398B2
申请日:
2010.06.24
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention relates to improved Nanobodies™ against von Willebrand Factor (vWF), as well as to polypeptides comprising or essentially consisting of one or more of such Nanobodies. The invention also relates to nucleic acids encoding such Nanobodies and polypeptides; to methods for preparing such Nanobodies and polypeptides; to host cells expressing or capable of expressing such Nanobodies or polypeptides; to compositions comprising such Nanobodies, polypeptides, nucleic acids or host cells; and to uses of such Nanobodies, such polypeptides, such nucleic acids, such host cells or such compositions, in particular for prophylactic, therapeutic or diagnostic purposes, such as the prophylactic, therapeutic or diagnostic purposes.
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