Extended Release Compositions Comprising Hydrocodone And Acetaminophen For Rapid Onset And Prolonged Analgesia That May Be Administered Without Regard To Food
Krishna R. Devarakonda,Michael J. Giuliani,Vishal K. Gupta,Ralph A. Heasley,Susan Shelby
申请号：
US14187939
公开号：
US20140288113A1
申请日:
2014.02.24
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present disclosure provides an extended release pharmaceutical composition comprising hydrocodone and acetaminophen that provides a rapid onset of analgesia, and reduced levels of acetaminophen near the end of the dosing interval. Also provided are methods for reducing the risk of acetaminophen-induced hepatic damage in a subject being treated with an acetaminophen containing composition, as well as methods for treating pain in a subject in need thereof.
