A device (1) for freezing adipose tissue comprises a first member (2) and a second member (3) which are mutually coupleable so as to obtain at least one closed configuration; the first member comprising at least one manual grip portion (4) and at least one support portion (5) to which the adipose tissue adheres; the second member comprising at least one housing (6) wherein at least the support portion of the first member is insertable. The second member comprises at least one safety valve (20) that comprises at least one separable portion (21) adapted to detach, partially or completely, from the body of said second member in the case the pressure difference between the inside and the outside exceeds a predetermined value. The second member comprises retention means (24) of the separable portion (21) once it has detached. The detachment of the separable portion creates an opening (26) in the second member, and a gap (25) is defined for the discharge of the gases contained within the housing (6).