ERRICHELLI, Lorenzo,GUPTA, Dhanu,HEAN, Justin,NORDIN, Joel
申请号：
AU2018365299
公开号：
AU2018365299A1
申请日:
2018.11.08
申请国别(地区):
AU
年份:
2020
代理人:
摘要：
The present invention pertains to extracellular vesicle (EV) therapeutics, wherein the EVs comprise nucleic acid (NA)-based therapeutics such as m RNAs, circular RNAs, mi RNAs, sh RNAs, circular RNA and/or DNA molecules. The NA therapeutics are loaded into EVs using inventive engineering protein and NA engineering strategies to enhance loading into EVs and to facilitate release of the NA cargo molecules inside target cells.
