LEE, BYUNG KYU,LEE, KANG JIN,KIM, MINJOONG,PARK, HONGGYU
申请号：
CA2949653
公开号：
CA2949653A1
申请日:
2015.05.29
申请国别(地区):
CA
年份:
2015
代理人:
摘要：
The present invention relates to: a novel cell penetrating peptide； a cell penetrating botulinum toxin recombinant protein composition in which the cell penetrating peptide and the light chain of a botulinum toxin are fused； and a use thereof and, more specifically, to a composition enabling the transdermal delivery of a cell penetrating botulinum toxin recombinant protein and capable of being locally used for various treatments of the skin and cosmetic purposes. The cell penetrating peptide-botulinum toxin recombinant protein of the present invention can be transdermally delivered, thereby having the intrinsic effect of a botulinum toxin and simultaneously having greater convenience of use, and thus can be effectively applied as a local agonist for the treatment of various diseases and aesthetic and/or cosmetic purposes.
