SEGANISH, W. MICHAEL,MCELROY, WILLIAM, T.,BRUMFIELD, STEPHANIE,HERR, R. JASON,YET, LARRY,YANG, JINHAI,HARDING, JAMES, P., III,HO, GINNY DAI,TULSHIAN, DEEN, B.,YU, WENSHENG,WONG, MICHAEL, K. C.,LAVEY,
申请号：
EP13845875
公开号：
EP2903617A4
申请日:
2013.10.03
申请国别(地区):
EP
年份:
2016
代理人:
摘要：
The present invention relates to compounds which modulate interleukin-1 (IL-1) receptor-associated kinase 4 (IRAK4) and are useful in the prevention or treatment of inflammatory, cell proliferative and immune-related conditions and diseases. Specifically, provided herein are inhibitors of IRAK4 of Formula I and pharmaceutical compositions comprising such inhibitors, as well as methods therewith for treating IRAK4-mediated or -associated conditions or diseases.
